Flagship Labs 111: Cell Biology Co-Op

Company Description

Flagship Labs 111 Inc. (FL111) is a privately held, early-stage biotechnology company pioneering a novel platform harnessing innovations in chemistry, computation, and data science to create new therapeutic modalities beyond traditional small molecules. FL111 is backed by Flagship Pioneering, bringing the courage, vision, and resources to guide FL111 from platform validation to patient impact. We are seeking collaborative, creative and relentless problem solvers that share our passion for impact to join us! The Role Design and execute cell-based experiments characterizing novel heterobifunctional molecules in cancer cell models. Maintain, expand, and qualify a panel of cancer cell lines for ongoing studies. Plan and run compound treatment experiments, including concentration-response, time-course, and combination studies. Execute cell proliferation and viability assays to evaluate cellular response to treatment. Perform Western blotting, qPCR, ELISA, and other cell-based PD assays to assess target engagement, pathway modulation, and downstream molecular effects. Analyze data, generate figures and summaries, and interpret results against experimental hypotheses. Review results with the team; help identify follow-up experiments, controls, and troubleshooting steps. Develop, optimize, and document protocols to support reproducible execution across studies. Maintain complete, accurate records in an electronic lab notebook (ELN) — conditions, calculations, observations, deviations, raw data, and conclusions. Present findings to scientists and project teams; collaborate with biology and chemistry colleagues on experimental planning and molecule characterization.

Key Responsibilities

By the end of the co-op, you will have contributed to a reproducible experimental workflow generating decision-quality data, evidenced by: Cell lines consistently maintained and used with sound culture practice and documentation. PD datasets with appropriate vehicle and po