2027 Future Talent Program – Development of a Multiplex Antibody-Dependent Cellular Phagocytosis – Intern

Job Description

The Future Talent Program features internships that last up to 12 weeks and will include one or more projects. These opportunities in our Research and Development Division can provide you with great development and a chance to see if we are the right company for your long-term goals. Position Description The Exploratory Vaccines-Regulated Bioanalytics group supports vaccine research and development by designing and implementing innovative immunological assays used to characterize vaccine-induced immune responses. We develop and apply functional bioanalytical platforms that help advance vaccine candidates from discovery through clinical development. The successful candidate will contribute to the development of a novel multiplex antibody-dependent cellular phagocytosis (ADCP) assay designed to simultaneously evaluate functional antibody responses against multiple respiratory vaccine antigens. This internship offers a unique opportunity to gain hands-on experience in immunology assay development, flow cytometry, vaccine bioanalytic, and data analysis while working alongside scientists supporting cutting-edge vaccine programs. Project Overview Antibody-dependent cellular phagocytosis (ADCP) is an important antibody effector function that contributes to vaccine-induced immunity. Current ADCP testing is performed in a singleplex format, requiring independent analysis of each vaccine antigen. The goal of this project is to establish a bead-based multiplex ADCP platform capable of simultaneously measuring functional antibody responses against multiple antigens. The intern will perform proof-of-concept studies to evaluate multiplex assay feasibility, optimize assay conditions, generate and analyze experimental data, and compare multiplex assay performance to established singleplex methods. This work has the potential to improve assay throughput, reduce sample and reagent consumption, and expand functional immunogenicity assessment capabilities for multivalen