Bioinformatics Co-op (Spring 2027)

Wave Life Sciences is a biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health. Our RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation and deep insights in human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Our toolkit of RNA-targeting modalities including RNAi silencing and RNA editing provides us with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. Our diversified pipeline is focused on our obesity, alpha-1 antitrypsin deficiency and PNPLA3 I148M liver disease programs and includes clinical programs for Duchenne muscular dystrophy and Huntington’s disease, as well as several preclinical programs utilizing our versatile RNA medicines platform. Driven by the calling to “Reimagine Possible”, we are leading the charge toward a world in which human potential is no longer hindered by the burden of disease.

Description

Wave needs a highly motivated and detail-orientated individual to work in the areas of bioinformatics, computational biology and human genetics in support of Wave’s drug discovery programs. The candidate will be expected to work within a team to design and execute sequence-based machine learning projects that generate critical information for drug discovery and target assessment. The candidate will create and deploy data and test hypotheses related to human genetics and bioinformatics. The candidate will build and use the next generation of human genetics and bioinformatics tools for the development of oligonucleotide therapeutics. The candidate should have a strong coding and software development background and a willingness to work in an interdisciplinary team of chemists, biologists, and software developers.

Experience

• Discovery and development of oligonucleotide therapeutics is a plus
• Working with high-performance compute environments

Responsi